Dissertation Hamburg

J. Westendorf (1975) Die Kinetik der Acetylcholinesterasehemmung und die Beeinflussung der Permeabilität von Erythrozytenmembranen durch Fluorid und Fluorokomplexionen.

 

 

Originalarbeiten

1. A. Knappwost und J. Westendorf (1973) Fluorionen-Aufnahme und Vagotonie: Über die Hemmung der Acetylcholinesterase durch Fluor-Ionen Naturwiss., 60: 353-275

2. A. Knappwost und J. Westendorf (1974) Zur Hemmung der Acetylcholinesterase durch Fluorid Naturwiss., 61: 274-275

3. A. Knappwost und J. Westendorf (1975) Hemmung von Cholinesterasen durch Fluorokomplexe des Siliciums und des Eisens. Naturwiss., 61: 275-276

4. J. Westendorf und G. Czok (1978) Untersuchungen der Pharmakokinetik von 14C-Zimtsäurederivaten an Ratten. Z. Ernährungswiss., 17: 26-36

5. J. Westendorf (1979) Pharmakologische Bewertung von Urol. Fortschr. Urologie und Nephrologie, Suppl. 14: 13-18

6. J. Westendorf und W. Vahlensiek (1981) Spasmolytische unf kontraktile Einflüsse des pflanzlichen Kombinationspräparates UROL auf die glatte Muskulatur des isolierten Meerschweinchendarmes. Arzneim.-Forschung/Drug Res., 31: 40-43

7. J. Westendorf (1982) CARITO- In vitro Untersuchungen zum Nachweis spasmolytischer und kontraktiler Einflüsse auf die glatte Muskulatur sowie antibakterielle Effekte des pflanzlichen Kombinationspräparates.

8. H. Marquardt, J. Westendorf, and H. Marquardt (1982) Potent antiviral 2`-fluoroarabinosylpyrimidine nucleosides: lack of mutagenic activity. Carcinogenesis, 3: 593-596

9. H. Marquardt, J. Westendorf, and H. Marquardt (1982) Anthracycline antitumor antibiotics: Their carcinogenicity and their mutagenicity. In: F. Muggia, C.W. Young and S.K. Carter (eds.), Anthracycline Antibiotics In Cancer Therapy. Developments in Oncology, 10: 30-49; The Hague, M. Nijhoff Publishers

10. J. Westendorf und W. Vahlensiek (1983) Spasmoytische Einflüsse des pflanzlichen Kombinationspräparates UROL auf die isolierte Rattenharnblase. Therapiewoche, 33: 936-944

11. J. Westendorf, H. Marquardt, M.B. Ketkar, U. Mohr, and H. Marquardt (1983) Tumorigenicity in vivo and induction of mutagenesis and DNA repair in vitro by aclacinomycin A and marcellomycin: Structure activity relationship and predictive value of short-term-tests. Cancer Res., 43: 5248-5251

12. J. Westendorf und G. Czok (1983) Die biliäre Ausscheidung choleretisch aktiver Zimtsäurederivate durch die Ratte. Z. Ernährungswiss., 22: 255-270

13. J. Westendorf, H. Marquardt and H. Marquardt (1984) Structure activity relationship of anthracycline-induced genotoxicity. Cancer Res., 44: 5599-5604

14. J. Westendorf, G. Groth, G. Steinheider and H. Marquardt (1985) Formation of DNA-adducts and induction of DNA-crosslinks and chromosomal aberrations by the new potent anthracycline antitumor antibiotics: Morpholinodaunomycin, cyanomorpholinodaunomycin and cyanomorpholinoadriamycin. Cell Biol. Toxicol., 1: 87-101

15. H. Marquardt, J. Westendorf, E. DeClercq and H. Marquardt (1985) Potent antiviral 5-(2-bromovinyl)uracil nucleosides are inactive at inducing gene mutations in Salmonella typh. and Chinese hamster cells and unscheduled DNA synthesis in primary rat hepatocytes. Carcinogenesis, 6: 1207-1209

16. J. Westendorf, H. Marquardt and H. Marquardt (1986) DNA interaction and mutagenicity of the plastic stabilizer di-n-octyltin-dichloride. Arzneim.-Forsch./Drug Res., 36: 1263-1264

17. G. Steinheider, J. Westendorf and H. Marquardt (1986) Induction of erythroid differentiation by the anthracycline antitumor antibiotics aclacinomycin A, musettamycin and marcellomycin. Leucemia Res., 10: 1233-1239

18. J. Westendorf, U. Mohr and H. Marquardt (1987) Induction of malignant transformation in vitro and mammary tumors in rats by two new potent anthracycline antitumor antibiotics, morpholinodaunomycin and cyanomorpholinoadriamycin. Cell Biol. Toxicol., 3: 17-21

19. G. Steinheider, J. Westendorf and H. Marquardt (1987) Induction of chromosomal aberrations by the anthracycline antitumor antibiotics N,N-dimethyldaunomycin and Aclacinomycin A. Experientia, 43: 586-588

20. G. Steinheider, A. Schäfer, J. Westendorf and H. Marquardt (1988) Induction of erythroid differentiation by the anthracycline antitumor antibiotic pyrromycin. Cell Biol. Toxicol., 4: 123-133

21. J. Westendorf, B. Poginsky, H. Marquardt and H. Marquardt (1988) The genotoxicity of Lucidin, a natural component of Rubia tinctorum L. and lucidinethylether, a component of ethanolic Rubia extracts. Cell Biol. Toxicol., 4: 225-239

22. A. Schäfer, J. Boldt, J. Westendorf, G. Steinheider and H. Marquardt (1988) Inhibition of amino acid uptake and protein synthesis in Friend erythroleucemia cells by the anthracycline antitumor antibiotic aclacinomycin A Biochem. Pharmacol., 37: 1377-1382

23. B. Poginsky, J. Westendorf, N. Prosenc, M. Kuppe and H. Marquardt (1988) Johanniskraut: Genotoxizität bedingt durch den Quercetingehalt. Deutsche Apotheker Ztg., 128: 1364-1365

24. H. Marquardt, J. Westendorf, A. Schäfer, J. Boldt, E. DeClercq and H. Marquardt (1988) Mutagenic and antimutagenic effects of 5-substituted 2′-deoxyuridines depending on the nature of the 5′-substituent. Arzneim.-Forsch./Drug Res., 38: 1820-1824

25. J. Westendorf, M. Aydin, G. Groth, O. Weller and H. Marquardt (1989) Mechanistic aspects of DNA damage by morpholino- and cyanomorpholinoanthracyclines. Cancer Res., 49: 5262-5266

26. J. Westendorf, H. Marquardt, B. Poginsky, M. Dominiak, J. Schmidt and H. Marquardt (1990) Genotoxicity of naturally occurring hydroxyanthraquinones. Mut. Res., 240: 1-12

27. D. Wölfle, Ch. Schmutte, J. Westendorf and H. Marquardt (1990) Hydroxyanthraquinones as tumorpromotors: Enhancement of malignant transformation of C3H-mouse fibroblasts and growth stimulation of primary rat hepatocytes. Cancer Res., 50: 6540-6544

28. B. Poginsky, J. Westendorf, B. Blömeke, H. Marquardt, A. Hewer, P. Grover and D. Phillips (1991) Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum Carcinogenesis, 12: 1265-1271

29. B. Blömeke, B. Poginsky, Ch. Schmutte, H. Marquardt and J. Westendorf (1992) Formation of genotoxic metabolites from anthraquinone gylcosides present in Rubia tinctorum L. Mutation Res., 265: 263-272

30. C. Odefey, J. Westendorf, Th. Dieckmann and H. Oschkinat (1992) Two-dimensional NMR studies of an intercalation complex between the novel semisynthetic anthracycline 3′-deamino-3′-(2-methoxy-4-morpholinyl)-doxorubicin and the hexanucleotide duplex d(CGTACG). Chem. Biol. Interact., 85: 117-126

31. A. Schäfer, J. Westendorf, K. Lingelbach, C. Schmidt, D. Mihalace, A. Reymann and H. Marquardt (1993) Decreased resistance to N,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleucemia cells. Cancer Chemother Pharmacol., 31: 301-307

32. U. Steinhorst, E. Chen, D. Hatchell, G. Samsa, P. Saloupis, J. Westendorf, and R. Machemer (1993) Aclacinomycin A in the Treatment of experimental proliferative vitreoretinopathy. Invest Ophtalm Visual Science 34: 1753-1760

33. H. Helmholz, A. Ruge, A. Piasecki, Sabine Schröder und Johannes Westendorf (1993) Genotoxizität der Faulbaumrinde Pharm Ztg 138 (43): 48-50

34. J. Westendorf (1993) Pharmakologische und toxikologische Bewertung von Anthranoiden PZ 138: 9-20

35. H.-H. Vahl und Johannes Westendorf (1994) Genotoxizität von frisch abgelagerten schwebstoffbürtigen Sedimenten aus der Elbe. Festphasentest zur Beurteilung des cancerogenen und mutagenen Potentials. Berichte aus dem Zentrum für Meeres- und Klimaforschung, Hamburg,7: 47-52

36. J. Borchert und J. Westendorf (1994) Kinetik der Aufnahme und Metabolisation von sedimentgebundenem Benzo(a)pyren in Benthosorganismen Berichte aus dem Zentrum für Meeres- und Klimaforschung, Hamburg,7: 53-55

37. Pfau, W., Jedamski.Grymlas, K., Söhren, K.-D., Westendorf, J., Marquardt H., und Karbe, L. (1994) DNA Addukte in der Leber von Brassen (Abramis, brama) aus der Elbe. Berichte aus dem Zentrum für Meeres- und Klimaforschung, Hamburg,7: 75-79

38. Liepelt, A. Karbe, L. und Westendorf J. (1994) DNA Strangbrüche in Fischen aus der Elbe und Befunde aus Laborexperimenten zur Induktion von DNA Schäden durch Hypoxie und Hyperoxie. Berichte aus dem Zentrum für Meeres- und Klimaforschung, Hamburg,7: 81-86

39. Liepelt A., Karbe L. and Westendorf J. (1995) Induction of DNA strand breaks in rainbow trout Oncorynchus mykiss under hypoxic and hyperoxic conditions. Aquatic Toxicol 33 (2): 177-181

40. Vahl, H.H., Karbe, L., Prieto-Alamo, M.J., Pueyo, C. and Westendorf, J. (1995) The use of the Salmonella BA9 forward mutation assay in sediment quality assessment. Mutagenicity of freshly deposited sediments of the River Elbe. J Aquat Ecosyst Health 4: 277-283

41. Berger, B., Marquardt, H. and Westendorf, J. (1996) Pharmacological and Toxicological Aspects of New Imidazoacridinone Antitumor Agents Cancer Research 56: 2094-2104

42. Borchert J. Karbe, L. and Westendorf, J. (1997) Uptake and Metabolism of Benzo[a)pyrene absorbed to a standard sediment by the Freshwater Invertebrate Species Chironomus riparius (M.) and Sphaerium corneum Bull Environm Contam Toxicol 58: 158-165

43. Vahl, H.-H., Karbe, L. and Westendorf, J. (1997) Genotoxicity assesment of suspended particulate matter in the Elbe River: comparison of Salmonella microsome test, arabinose resistance test, and umu-test Mutation Research 394: 81-93

44. Westendorf, J., Pfau, W. and Schulte, A. (1998) Carcinogenicity and DNA adduct formation observed in ACI rats after long term treatment with madder root, Rubia tinctorum, L. Carcinogenesis 19: 2163-2168

45. Paneitz, A. and Westendorf, J. (1999) Anthranoid contents of Rhubarb (Rheum undulatum L.) and other Rheum species and its toxicological relevance. Eur Food Res Technol 210: 97-101

46. Meyer, F, Fiala, E. and Westendorf, J. (2000) Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress. Toxicology, 146, 83-92

47. Schehrer, L., Regan, J., and Westendorf, J. (2000) UDS-induction by an array of standard carcinogens in human and rodent hepatocytes: effect of cryopreservation Toxicology 147, 177-191

48. Westendorf, J., and Regan, J. (2000) Induction of DNA-strand breaks in primary rat hepatocytes by ginkgolic acids Pharmazie 55, 864-865

49. Shen, J., Gutendorf, B., Vahl, H., Shen , L. and Westendorf, J. (2001) Toxicological profile of pollutants in surface water from an area in Taihu lake, Yangtze delta Toxicology 166, 71-78

50. Gutendorf, B. and Westendorf, J. (2001) Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology, 166, 79-89

51. Chukhlovin, A., Tokalov, S., Yagunov, A., Westendorf, J., Reincke, H., Karbe, L. (2001) In vitro suppression of thymocyte apoptosis by metal-rich complex environmental mixtures: potential role of zinc and cadmium excess. The Science of the total environment 281, 153-163

52. Katzer, A., Marquardt, H., Westendorf, J., Wening, J., von Foerster, G. (2002) Polyetherketone-cytotoxicity and mutagenicity in vitro Biomaterials 23, 1749-1759

53. Huehnerfuss, H., Bergman, A., Larsson, C., Peters, N., Westendorf, J. (2003) Enantioselective transformation of atropisomeric PCBs or of their methylsulfonyl metabolites by rat hepatocytes? Organohalogen compounds, 60-65, Dioxin 2003 Boston, MA

54. Effenberger, . K.E., Johnsen, S.A, Monroe, D.G. Spelsberg, T.C. and Westendorf, J.J. (2005) Regulation of osteoblastic phenotype and gene expression by hop-derived phytoestrogens Journal of Steroid Biochemistry and Molecular Biology 96, 387-399

55. Kammann U, Biselli S, Reineke N, Wosniok W, Danischewski D, Hühnerfuss H, Kinder A, Sierts-Herrmann A, Theobald N, Vahl HH, Vobach M, Westendorf J, Steinhart H (2005) Bioassay-directed fractionation of organic extracts of marine surface sediments from the North and Baltic Sea – Part II: Results of the biotest battery and development of a biotest index. J Soils & Sediments, 5 (4) 225-232

56. W. Gaus, J. Westendorf, R. Diebow, M. Kieser (2005) Identification of adverse drug reactions by evaluation of a prescription database, demonstrated for the „risk of bleeding“ Methods Inf Med 2005, Vol 44, p.697–703

57. Ismene Jäger, Christoph Hafner, Claudia Welsch, Klaus Schneider, Hassan Iznaguen, Johannes Westendorf (2006) The mutagenic potential of madder root in dyeing processes in the textile industry Mutation Research 605, 22-29

58. B.J.West, C.J. Jensen, J. Westendorf, and L.D. White (2006) A Safety Review of Noni Fruit Juice J Food Science , 2006,71, 100-106

59. Johannes Westendorf, Katharina Effenberger, Hassan Iznaguen, Simla Basar (2007) Toxicological and analytical investigations of Noni (Morinda citrifolia) fruit juice. J. Agric. Food Chem. 2007, 55, 529-537

60. Brett J. West, Claude C. Jensen and J. Westendorf (2008) A new vegetable oil from Noni (Morinda citrifolia) seeds. Intern J Food Sci Technol, 2008, 43, 1988-1992

61. Deng, S., West, B.J., Jensen, C.J., Basar, S., & Westendorf, J. (2009) Development and validation of an RP-HPLC method for the analysis of anthraquinones in noni fruits and leaves. Food Chemistry, 116, 505-508

62. Basar, S., Uhlenhut, K., Högger, P., Schöne, F., Westendorf, J. (2009) Analgesic and anti-inflammatory activity of Morinda citrifolia L. (Noni) fruit. Phytother Res 24: 38-42 Published online in Wiley InterScience (www.interscience.wiley.com) DOI: 10.1002/ptr.2863

63. Westendorf, J. and Mettlich, C. (2009) The benefits of noni juice: an epidemiological evaluation in Europe. Journal of Medicinal Food Plants Vol. 1(2), 64–79

64. Brett J. West, Leland D. White, , C. Jarakae Jensen, Afa K. Palu, and J. Westendorf (2009) A Double-Blind Clinical Safety Study of Noni Fruit Juice. Pacific Health Dialog, VOL. 15 (2), 21-32

65. Basar, S. and Westendorf, J. (2011) Identification of (2E,4Z,7Z)-Decatrienoic Acid in Noni Fruit and Its Use in Quality Screening of Commercial Noni Products. Food Anal. Methods. 4(1) 57-65 DOI 10.1007/s12161-010-9125-9

66. Basar, S. and Westendorf (2012)   Concentrations in Morinda citrifolia L. (Noni) Leaf, Fruit and Fruit Juice” Food and Nutrition Sciences, 3, 1176-1188

 

Buchbeiträge

1. J. Westendorf (1992) a) Pyrrolizidine-Alkaloids In: P.A.C.M. De Smet, K. Keller, R. Hänsel, R.F. Chandler (eds.) Adverse Effects of Herbal drugs, Vol. I, Springer Verlag, Berlin, Heidelberg, New York, Tokyo; 193-226

2. J. Westendorf (1993) a) Anthranoids In: P.A.C.M. De Smet, K. Keller, R. Hänsel, R.F. Chandler (eds.) Adverse Effects of Herbal drugs, Vol. I, Springer Verlag, Berlin, Heidelberg, New York, Tokyo; 105-139

3. J. Westendorf (1993) Außerplanmäßige DNA-Synthese (UDS). In: R. Fahrig (ed.) Mutationsforschung und genetische Toxikologie. Wissenschaftliche Buchgesellschaft, Darmstadt; 199-206

4. J. Westendorf (1994) Natürliche Gifte- Tierische Gifte, Mykotoxine, Pflanzengifte- In: S. Schäfer und H. Marquardt (eds.) Lehrbuch der Toxikologie Wissenschaftsverlag, Mannheim, Leipzig, Wien, Zürich, pp 650-691

5. J. Westendorf (1999) Natural Compounds In: H. Marquardt, S. Schäfer, R. McClellan, F. Welsch (eds.) Toxicology Academic Press, San Diego, London, New York, Sydney, Tokyo, Toronto, pp 959-1007

6. J. Westendorf (2000) Komplexe Wirkungen von Xenobiotika in Gewässern-Genotoxische Wirkungen In: R. Guderian (ed.) Handbuch der Umweltveränderungen und Ökotoxikologie Springer Verlag, Berlin Heidelberg, pp. 342-350

7. J. Westendorf (2000) Umwelttoxikologie In: Innere Medizin Georg Thieme Verlag, Stuttgart, New York pp. 2029-2031

8. J. Westendorf (2004) Natürliche Gifte- Tierische Gifte, Mykotoxine, Pflanzengifte- In: S. Schäfer und H. Marquardt (eds.) Lehrbuch der Toxikologie, 2. Auflage Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, pp 1025-1073